Rods Feed Cones to Keep them Alive
نویسندگان
چکیده
Cone photoreceptors, responsible for high-resolution and color vision, progressively degenerate following the death of rod photoreceptors in the blinding disease retinitis pigmentosa. Aït-Ali et al. describe a molecular mechanism by which RdCVF, a factor normally released by rods, controls glucose entry into cones, enhancing their survival.
منابع مشابه
Identification of differentially expressed genes in carp rods and cones
PURPOSE Rods and cones differ in their photoresponse characteristics, morphology, and susceptibilities to certain diseases. To contribute to the studies at the molecular level of these differences, we tried to identify genes expressed preferentially in rods or cones. METHODS From purified carp rods and cones, we extracted their RNA and obtained corresponding cDNA pools (rod cDNA and cone cDNA...
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Rods and cones are both photoreceptors in the retina, but they are different in many aspects including the light response characteristics and, for example, cell morphology and metabolism. These differences would be caused by differences in proteins expressed in rods and cones. To understand the molecular bases of these differences between rods and cones, one of the ways is to compare proteins e...
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Goldfish were placed on a daily light cycle of 12 h light and 12 h darkness for 18 days or longer. The visual cells and pigment epithelium of the retina were then examined by microscopy at many intervals throughout the cycle. Goldfish rods and cones follow a rhythmic pattern in eliminating packets of photosensitive membranes from their outer segments. Rods shed membranes early in the light peri...
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ورودعنوان ژورنال:
- Cell
دوره 161 شماره
صفحات -
تاریخ انتشار 2015